PUBLICATIONS

2023

57. Siqiang Fang,† Jiajia He,† Zanjiao Liu, Zhishan Su,* Fengyuan Guo, and Tianli Wang* “Atherton-Todd Reaction-Guided Enantioselective Synthesis of Axially Chiral Olefins via Bifunctional Phosphonium Salt-Regulating Ketone-Enol Tautomerism" ACS Catal. 2023, 13, 13077−13088.
56. Fengyuan Guo,⁺ Siqiang Fang,⁺ Jiajia He,⁺Zhishan Su* and Tianli Wang* "Enantioselective Organocatalytic Synthesis of Axially Chiral Aldehyde-containing Styrenes via S_NAr Reaction-Guided Dynamic Kinetic Resolution" Nat. Commun. 2023, 14, 5050.
55. Hui-Lin Hu,⁺ Siqiang Fang,⁺ Yulin Chen, Wei Wan, Yuqiao Zhou, Zhipeng Xu,* Tianli Wang* "Access to Phosphorous-containing Cyclopenta[b]benzofuranols via Bifunctional Phosphonium Salt-promoted Serendipitous Cascade Reaction" Org. Chem. Front. 2023, DOI:10.1039/D3QO00979C.
54. Siqiang Fang⁺, Zanjiao Liu⁺, Tianli Wang* "Design and Application of Peptide-Mimic Phosphonium Salt Catalysts in Asymmetric Synthesis" Angew. Chem. Int. Ed. 2023, 62, e202307258.
53. Siqiang Fang, Zanjiao Liu, Tianli Wang* "Recent Advances of the Atherton-Todd Reaction" Chin. J. Org. Chem. 2023, 43, 1069-1083.
52. Jixing Che,⁺ Siqiang Fang,⁺ Jianke Pan,Lixiang Zhu, Xiaoyu Ren, and Tianli Wang* "Asymmetric Mannich/Radical Debromination Cascade of a-Bromoketones by Dipeptide-Phosphonium Salt Catalysis: Enantioselective Synthesis of β-Amino Ketone-Pyrazolinones" Asian J. Org. Chem 2023, 12, e202300079.
(selected as Front Cover by Asian J. Org. Chem.)
51. Jia-Hong Wu,⁺ Jian-Ping Tan,⁺ Jia-Yan Zheng,⁺ Jiajia He, Zhenlei Song,* Zhishan Su, Tianli Wang* "Towards Axially Chiral Pyrazole-Based Phosphorus Scaffolds by Dipeptide-Phosphonium Salt Catalysis" Angew. Chem. Int. Ed. 2023, 62, e202215720.
(highlighted by Chin. J. Org. Chem. 2023, 43, 1208 and Chem. Catal. 2023, 3, 100579.)

2022

50. Kehan Li,⁺ Dongming Lu,⁺ Jian-Ping Tan,* Xiaoyu Ren, Tianli Wang* "Chemoselective Annulation of 2-Benzothiazolimines Enabled by Bifunctional Phosphonium Salt: Highly Enantioselective Synthesis of Indole-fused Cyclic Thiourea Scaffolds" Asian J. Org. Chem. 2022, 11, e202200368.
49. Hui-Lin Hu,⁺ Xiaoyu Ren,⁺ Jiajia He, Lixiang Zhu, Siqiang Fang, Zhishan Su, Tianli Wang* "Stereodivergently Asymmetric Synthesis of Chiral Phosphorus Compounds by Synergistic Combination of Ion-pair Catalyst and Base" Sci. China Chem. 2022, 65, 2500-2511.
48. Yuan Chen,⁺ Jiajia He,⁺ Cheng Zhuang,Zanjiao Liu, Kai Xiao, Zhishan Su,* Xiaoyu Ren, and Tianli Wang* "Synergistic Catalysis between a Dipeptide Phosphonium Salt and a Metal-Based Lewis Acid for Asymmetric Synthesis of N-Bridged [3.2.1] Ring Systems" Angew. Chem. Int. Ed. 2022, 61, e202207334.
(Selected as the Inside Back Cover by Angew Chemie)
47. Lixiang Zhu,⁺ Heling Peng,⁺ Yan Guo, Jixing Che, Jia-Hong Wu, Zhishan Su, and Tianli Wang* "Enantioselective Synthesis of Atropisomeric Biaryl Phosphorus Compounds by Chiral Phosphonium-Salt-Enabled Cascade Arene Formation" Angew. Chem. Int. Ed. 2022, 61, e202202467.
46. Jian-Ping Tan,⁺ Kehan Li,⁺ Boming Shen,⁺ Cheng Zhuang, Zanjiao Liu, Kai Xiao, Peiyuan Yu*, Bing Yi,* Xiaoyu Ren and Tianli Wang* "Asymmetric synthesis of N-bridged [3.3.1] ring systems by phosphonium salt/Lewis acid relay catalysis" Nat. Commun. 2022, 13, 357.
(highlighted by Benjamin List, Synfacts, 2022, 18, 666.)
45. Xuemei Wang,⁺ Liang Zhou,⁺ Hongkui Zhang, Xiaoyu Ren,* Guowei Gao, and Tianli Wang* "Enantioselective γ‑Addition-Driven Cascade of β,γ-Unsaturated Ketones by Ion-Pair Catalysis: Access to Chiral 1,3-Dioxolochroman Scaffolds" Org. Lett. 2022, 24, 38-42.
44. Jian-Ping Tan,⁺ Yuan Chen,⁺ Xiaoyu Ren,* Yumeng Guo, Bing Yi,* Hongkui Zhang, Guowei Gao, and Tianli Wang* “In situ phosphonium-containing Lewis base-catalyzed 1,6-cyanation reaction: facile way to α-diaryl and α-triaryl acetonitriles” Org. Chem. Front. 2022, 9, 156-162.

2021

43. Yuan Chen,⁺ Zhaoyuan Yu,⁺ Zhiyu Jiang,⁺ Jian-Ping Tan, Jia-Hong Wu, Yu Lan,* Xiaoyu Ren, and Tianli Wang* "Asymmetric Construction of Tertiary/Secondary Carbon− Phosphorus Bonds via Bifunctional Phosphonium Salt Catalyzed 1,6-Addition" ACS Catal. 2021, 11, 14168−14180.
42. Siqiang Fang, Zanjiao Liu, Hongkui Zhang, Jianke Pan, Yuan Chen, Xiaoyu Ren, and Tianli Wang* "Access to S‑Stereogenic Free Sulfoximines via Bifunctional Phosphonium Salt-Catalyzed Desymmetrization of Bisphenols" ACS Catal. 2021, 11, 13902−13912.
41. Hongkui Zhang,⁺Jiajia He,⁺Yayun Chen,⁺ Cheng Zhuang, Chunhui Jiang,* Kai Xiao, Zhishan Su,* Xiaoyu Ren, and Tianli Wang* “Regio- and Stereoselective Cascade of β,γ-Unsaturated Ketones by Dipeptided Phosphonium Salt Catalysis: Stereospecific Construction of Dihydrofuro-Fused [2,3-b] Skeletons” Angew. Chem. Int. Ed. 2021, 60，19860-19870.
40. Zhenghuai Feng, Hongkui Zhang, Xiaoyu Ren,* Chunhui Jiang, Guowei Gao and Tianli Wang* "Enantioselective Construction of Tertiary C(sp3)-P Bonds by Thiourea-based Bifunctional Phosphonium Salt-catalyzed Hydrophosphonylation of Ketone Compounds" ChemCatChem. 2021, 13, 3754-3760.
39. Song Zhang,⁺ Zhenghuai Feng,⁺Chunhui Jiang*, Xiaojun Yu, Jianke Pan, Juan Du, Zhiyu Jiang, Yuan Chen, and Tianli Wang* "Highly Enantioselective Synthesis of Phosphorus-containing e-Benzosultams via Bifunctional Phosphonium Salt-promoted Hydrophosphonylation" Chem. Eur. J. 2021, 27, 11285-11290.
38. Zhiyu Jiang,⁺ Xin Liu,⁺ Hongkui Zhang, Jian-Ping Tan, Xiaoyu Ren*, Guowei Gao, Tianli Wang* "Asymmetric Cyclodearomatization of 2-Nitroindoles and 2-Nitrobenzofurans for Constructing CF₃-containing Spiro-polycycles by Bifunctional Phosphonium Salt Catalysis" Adv. Synth. Catal. 2021, 363, 3115-3120.
37. Siqiang Fang,⁺ Jian-Ping Tan,⁺ Jianke Pan, Hongkui Zhang, Yuan Chen, Xiaoyu Ren, Tianli Wang* "Enantiodivergent Kinetic Resolution of 1,1'-Biaryl-2,2'-Diols and Amino Alcohols by Dipeptide-Phosphonium Salt Catalysis Inspired by the Atherton-Todd Reaction" Angew. Chem. Int. Ed. 2021, 60, 14921-14930.
(Selected as the Frontispiece and Hot Paper by Angew Chemie)

2020

36. Lixiang Zhu, Xiaoyu Ren, Juan Du, Jia-Hong Wu, Jian-Ping Tan, Jixing Che, Jianke Pan, Tianli Wang* “Transition metal-free multicomponent reaction towards constructing chiral 2H-1,4-benzoxazine scaffolds” Green Chem. 2020, 22, 7506-7512.
35. Dongming Lu, Jia-Hong Wu, Jianke Pan, Xue Chen, Xiaoyu Ren, Tianli Wang* "Asymmetric Synthesis of Benzothiazolopyrimidines with High Catalytic Efficiency and Stereoselectivity under Bifunctional Phosphonium Salt System" Chem. Commun. 2020, 56, 11231-11234.
34. Jian-Ping Tan,⁺ Xiaojie Li,⁺ Yuan Chen, Xianle Rong, Lixiang Zhu, Chunhui Jiang, Kai Xiao, Tianli Wang* "Highly Stereoselective Construction of Polycyclic Benzofused Tropane Scaffolds and Their Latent Bioactivities: Bifunctional Phosphonium Salt-enabled Cyclodearomatization Process" Sci. China Chem. 2020, 63, 1091-1099.
- 33. Hongkui Zhang,⁺ Chunhui Jiang,⁺ Jian-Ping Tan, Hui-Lin Hu, Yayun Chen, Xiaoyu Ren, Hong-Su Zhang, Tianli Wang* “Highly Enantioselective Construction of Fully-substituted Stereocenters Enabled by In-situ Phosphonium-containing Organocatalysis” ACS Catal. 2020, 10, 5698-5706.
- (Highted by B. List*, Synfacts, 2020, 16, 0967)
32. Xiaojun Yu, Song Zhang, Zhiyu Jiang, Hong-Su Zhang, Tianli Wang* “Highly efficient and convenient access to phosphinates via CHCl₃-assisted direct phosphorylation between R₂P(O)H and ROH by phosphonium salt catalysis” Eur. J. Org. Chem. 2020, 20, 3110-3113.
31. Juan Du, Jia-Hong Wu, Lixiang Zhu, Xiaoyu Ren, Chunhui Jiang, Tianli Wang* "Bifunctional Phosphonium Salt-Catalyzed Enantioselective [4 + 2] Annulation of Isoindigos with Allenes: Access to Complex Heterocycles with Centerpiece of 4H-Pyrans." Adv. Synth. Catal. 2020, 362, 2510-2516.
30. Dongming Lu, Xin Liu, Jia-Hong Wu, Song Zhang, Jian-Ping Tan, Xiaojun Yu, Tianli Wang* “Asymmetric Construction of Bispiro‐Cyclopropane‐Pyrazolones via a [2 + 1] Cyclization Reaction by Dipeptide‐Based Phosphonium Salt Catalysis” Adv. Synth. Catal. 2020, 362, 1966-1971.
(Very important，VIP paper)
29. Xin Liu, Dongming Lu, Jia-Hong Wu, Jian-Ping Tan, Chunhui Jiang, Guowei Gao,* Tianli Wang* “Stereoselective Synthesis of CF₃-Containing Spirooxindoles via 1,3-Dipolar Cycloaddition by Dipeptide-Based Phosphonium Salt Catalysis” Adv. Synth. Catal. 2020, 3 62, 1490-1495.
(Very important，VIP paper)
28. Jia-Hong Wu, Jianke Pan, Juan Du, Xiaoxia Wang, Xuemei Wang, Chunhui Jiang, Tianli Wang.* “Enantioselective Synthesis of Multifunctionalized 4H-Pyrans via Formal [4 + 2] Annulation Process by Bifunctional Phosphonium Salt Catalysis” Org. Lett. 2020, 22, 395-399.
27. Jian-Ping Tan,⁺ Hongkui Zhang,⁺ Zhiyu Jiang, Yuan Chen, Xiaoyu Ren, Chunhui Jiang, Tianli Wang* “Enantioselective Construction of Spiro[chroman-thiazolones]: Bifunctional Phosphonium Salt-Catalyzed [2+4] Annulation between 5-Alkenyl Thiazolones and ortho-Hydroxyphenyl- Substituted para-Quinone Methides”. Adv. Synth. Catal. 2020, 362, 1058-1063.

2019

26. Chunhui Jiang,⁺ Yayun Chen,⁺ Hongkui Zhang, Jian-Ping Tan, Tianli Wang* "Catalyst-Free Synthesis of a-Functionalized 2H-Chromenes in Water:ATandem Self-Promoted pseudo-Substitution and Decarboxylation Process" Chem. Asian. J. 2019, 14, 2938-2944.
25. Jianke Pan,⁺ Jia-Hong Wu,⁺ Hongkui Zhang, Xiaoyu Ren, Jian-Ping Tan, Lixiang Zhu, HongSu Zhang, Chunhui Jiang, Tianli Wang* “Highly Enantioselective Synthesis of Fused Tri- and Tetrasubstituted Aziridines: aza-Darzens Reaction of Cyclic Imines with α-halogenated Ketones Catalyzed by Bifunctional Phosphonium Salt”. Angew. Chem. Int. Ed. 2019, 58, 7425-7430.
24. Jian-Ping Tan,⁺ Peiyuan Yu,⁺ Jia-Hong Wu, Yuan Chen, Jianke Pan, Chunhui Jiang, Xiaoyu Ren, HongSu Zhang, Tianli Wang.* “Bifunctional Phosphonium Salt Directed Enantioselective Formal [4+ 1] Annulation of Hydroxyl-Substituted Quinone Methides with α-halogenated Ketones” Org. Lett. 2019, 21, 7298-7302.
23. Lixiang Zhu,⁺ Xiaoyu Ren,⁺ Zhongxiu Liao, Jianke Pan, Chunhui Jiang, and Tianli Wang.* “Asymmetric Three-Component Cyclizations toward Structurally Spiro Pyrrolidines via Bifunctional Phosphonium Salt Catalysis”. Org. Lett. 2019, 21, 8667-8672.
22. Song Zhang,⁺ Xiaojun Yu,⁺ Jianke Pan, Chunhui Jiang,* Hongsu Zhang, Tianli Wang.* “Asymmetric Synthesis of Spiro-Structural 2,3-Dihydrobenzofurans via the Bifunctional Phosphonium Salt-Promoted [4 + 1] Cyclization of Ortho-Quinone Methides with α-Bromoketones” Org. Chem. Front. 2019, 6, 3799-3803.
21. Guofei Huang,⁺ Xiaoyu Ren,⁺ Chunhui Jiang, Jia-Hong Wu, Guowei Gao, Tianli Wang.* “Efficient Synthesis of (E)-2-Nitromethylcinnamates via Phosphine-Catalyzed Tandem α-Addition and 1,3-Rearrangement”. Org. Chem. Front. 2019, 6, 2872-2876.
20. Jia-Hong Wu,⁺ Jianke Pan,⁺ Tianli Wang* “Dipeptide-Based Phosphonium Salt Catalysis: Application to Enantioselective Synthesis of Fused Tri- and Tetrasubstituted Aziridines”. Synlett 2019, 30, 2101-2106.

Before 2018

19. Tianli Wang, Xiaoyu Han, Fangrui Zhong, Weijun Yao, and Yixin Lu,* “Amino Acid-derived Bifunctional Phosphines for Enantioselective Transformations”, Acc. Chem. Res. 2016, 49, 1369-1378.
18. Tianli Wang, Zhaoyuan Yu, Ding Long Hoon, Claire Yan Phee, Yu Lan, and Yixin Lu,* “Regiodivergent Enantioselective γ-Additions of Oxazolones to 2,3-Butadienoates Catalyzed by Phosphines: Synthesis of α,α-Disubstituted α-Amino Acids and N,O-Acetal Derivatives”, J. Am. Chem. Soc. 2016, 138, 265–271. ( Highlighted by Synfacts 2016, 12, 309).
17. Tianli Wang, Weijun Yao, Fangrui Zhong, Guo Hao Pang, Yixin Lu,* “Phosphine-Catalyzed Enantioselective γ-Addition of 3-Substituted Oxindoles to 2,3-Butadienoates and 2-Butynoates: Use of Prochiral Nucleophiles”, Angew. Chem. Int. Ed. 2014, 53, 2964-2968.
16. Tianli Wang, Fei Chen, Jie Qin, Yan-Mei He, Qing-Hua Fan,* “Asymmetric Ruthenium-Catalyzed Hydrogenation of 2- and 2,9-Substituted 1,10-Phenanthrolines”, Angew. Chem. Int. Ed. 2013, 52, 7172–7176. (Highlighted by Chin. J. Org. Chem. 2013, 33, 2028)
15. Tianli Wang, Lian-Gang Zhuo, Zhi Wei Li, Fei Chen, Zi Yuan Ding, Yanmei He, Qing-Hua Fan,* Jun Feng Xiang, Zhi-Xiang Yu,* Albert S. C. Chan, “Highly Enantioselective Hydrogenation of Quinolines Using Phosphine-Free Chiral Cationic Ruthenium Catalysts: Scope, Mechanism and Origin of Enantioselectivity”, J. Am. Chem. Soc. 2011, 133, 9878-9891.
14. Tianli Wang, Zhaoyuan Yu, Ding Long Hoon, Kuo-Wei Huang, Yu Lan,* Yixin Lu,* “Highly Enantioselective Construction of Tertiary Thioethers and Alcohols via Phosphine-Catalyzed Asymmetric γ-Addition reactions of 5H-Thiazol-4-ones and 5H-Oxazol-4-ones: Scope and Mechanistic Understandings”, Chem. Sci. 2015, 6, 4912-4922.
13. Tianli Wang, Ding Long Hoon, and Yixin Lu,* “Enantioselective Synthesis of 3-Fluoro-3-allyl-oxindoles via Phosphine-Catalyzed Asymmetric γ-Addition of 3-Fluoro-Oxindoles to 2,3-Butadienoates”, Chem. Commun. 2015, 51, 10186-10189.
12. Tianli Wang, Ya Chen, Guanghui Ouyang, Yan-Mei He,* Zhiyan Li and Qing-Hua Fan* “Solvent-Regulated Asymmetric Hydrogenation of Quinoline Derivatives in Oligo(Ethylene Glycol)s via Host-Guest Interactions”, Chem. Asian J. 2016, 11, 2773-2777.
11. Tianli Wang, Guanghui Ouyang, Yan-Mei He and Qing-Hua Fan,* “Asymmetric Tandem Reduction of 2-(Aroylmethyl)quinolines with Phosphine-Free Ru-TsDPEN Catalyst”, Synlett. 2011, 7, 939-942.
10. Zhen Wang,Tianli Wang,Weijun Yao, Yixin Lu.* “Phosphine-Catalyzed Enantioselective [4 + 2] Annulation of o-Quinone Methides with Allene Ketones”,Org. Lett. 2017, 19, 4126-4129
9. Xiaoyu Han, Weijun Yao, Tianli Wang, Yong Ren Tan, Ziyu Yan, Jacek. Kwiatkowski, Yixin. Lu,* “Asymmetric Synthesis of Spiropyrazolones through Phosphine-Catalyzed [4+1] Annulation”, Angew. Chem. Int. Ed. 2014, 53, 5643–5647.
8. Zi-Yuan Ding, Tianli Wang, Yan-Mei He, Fei Chen, Hai-Feng Zhou, Qing-Hua Fan,* Qingxiang Guo,* and Albert S. C. Chan, “Highly Enantioselective Synthesis of Chiral Tetrahydroquinolines and Tetrahydroisoquinolines by Ruthenium-Catalyzed Asymmetric Hydrogenation in Ionic Liquid”, Adv. Synth. Catal. 2013, 355, 3727-3735.
7. Fei Chen, Tianli Wang, Yanmei He, Ziyuan Ding, Zhiwei Li, Lijin Xu and Qing-Hua Fan,* "Asymmetric Hydrogenation of N-Alkyl Ketimines with Phosphine-Free, Chiral, Cationic Ru-MsDPEN Catalysts", Chem. -Eur. J. 2011, 17, 1109-1113.
6. Zhi-Wei Li, Tianli Wang, Yan-Mei He, Zhi-Jian Wang, Qing-Hua Fan,* Jie Pan and Li-Jin Xu,* "Air-Stable and Phosphine-Free Iridium Catalysts for Highly Enantioselective Hydrogenation of Quinoline Derivatives", Org. Lett. 2008, 10, 5265–5268.
5. Haifeng Zhou, Zhiwei Li, Zhijian Wang, Tianli Wang, Lijin Xu, Yanmei He, Qing-Hua Fan,* Jie Pan, Lianquan Gu and Albert S. C. Chan,* "Hydrogenation of Quinolines Using a Recyclable Phosphine-Free Chiral Cationic Ruthenium Catalyst: Enhancement of Catalyst Stability and Selectivity in an Ionic Liquid", Angew. Chem. Int. Ed. 2008, 47, 8464–8467.
4. Zhi-Jian Wang, Hai-Feng Zhou, Tianli Wang, Yan-Mei He, Qing-Hua Fan,* "Highly Enantioselective Hydrogenation of Quinolines under Solvent-Free or Highly Concentrated Conditions", Green Chem. 2009, 11, 767–769.
3. Fei Chen, Ziyuan Ding, Jie Qin, Tianli Wang, Yanmei He and Qing-Hua Fan,* "Highly Effective Asymmetric Hydrogenation of Cyclic N-Alkyl Imines with Chiral Cationic Ru-MsDPEN Catalysts", Org. Lett, 2011, 13, 4348–4351.
2. Weijun Tang, Yawei Sun, Lijin Xu,* Tianli Wang, Qing-Hua Fan, Kim-Hung Lam and Albert S. C. Chan, "Highly Efficient and Enantioselective Hydrogenation of Quinolines and Pyridines with Ir-Difluorphos Catalyst", Org. Biomol. Chem. 2010, 8, 3464–3471.
1. Fei Chen, Ziyuan Ding, Yanmei He, Jie Qin, Tianli Wang and Qing-Hua Fan,* "Asymmetric Hydrogenation of N-Alkyl and N-Aryl Ketimines using Chiral CationicRu(Diamine) Complexes as Catalysts: The Counteranion and Solvent Effects, and Substrate Scope", Tetrahedron 2012, 68, 5248-5257.